hu.MAP: Complex View

Human Protein Complex Map

Complex: 2401

Genename	Complexes	Protein Name	Links
TNFSF13B	2401 3724 4130	Tumor necrosis factor ligand superfamily member 13B (B lymphocyte stimulator) (BLyS) (B-cell-activating factor) (BAFF) (Dendritic cell-derived TNF-like molecule) (TNF- and APOL-related leukocyte expressed ligand 1) (TALL-1) (CD antigen CD257) [Cleaved into: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form]	UniProt NCBI
FAM118A	2401 3724	Protein FAM118A	UniProt NCBI
MAP3K5	2401 3724 4130	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5)	UniProt NCBI
MAP3K15	2401 3724 4130	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 3) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15)	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0004709	0.000279	0.5	MAP3K15 MAP3K5	MAP kinase kinase kinase activity
GO:0000186	0.000707	0.5	MAP3K15 MAP3K5	activation of MAPKK activity
GO:0004702	0.00633	0.5	MAP3K15 MAP3K5	signal transducer, downstream of receptor, with serine/threonine kinase activity
MI:hsa-miR-452	0.011	0.5	MAP3K15 TNFSF13B	MI:hsa-miR-452
GO:0005057	0.0138	0.5	MAP3K15 MAP3K5	signal transducer activity, downstream of receptor
KEGG:04672	0.0165	0.25	TNFSF13B	Intestinal immune network for IgA production
CORUM:5691	0.0167	0.25	TNFSF13B	TALL1 homo-oligomer complex
HPA:012010_02	0.017	0.75	MAP3K15 FAM118A TNFSF13B	endometrium 2; cells in endometrial stroma[Uncertain,Medium]
HPA:012010_01	0.0171	1.0	MAP3K15 MAP3K5 FAM118A TNFSF13B	endometrium 2; cells in endometrial stroma[Uncertain,Low]
HPA:040010_02	0.0235	0.75	MAP3K15 FAM118A TNFSF13B	soft tissue 2; adipocytes[Uncertain,Medium]
HPA:026020_01	0.0288	1.0	MAP3K15 MAP3K5 FAM118A TNFSF13B	ovary; ovarian stroma cells[Uncertain,Low]
GO:0032147	0.036	0.5	MAP3K15 MAP3K5	activation of protein kinase activity
KEGG:05014	0.0374	0.25	MAP3K5	Amyotrophic lateral sclerosis (ALS)
KEGG:05323	0.0397	0.25	TNFSF13B	Rheumatoid arthritis
GO:1990604	0.0471	0.25	MAP3K5	IRE1-TRAF2-ASK1 complex
GO:0043405	0.05	0.5	MAP3K15 MAP3K5	regulation of MAP kinase activity
REAC:5676594	0.05	0.25	TNFSF13B	TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
TF:M00264_1	0.05	0.5	MAP3K15 FAM118A	Factor: Staf; motif: MNTTCCCAKMATKCMWNGCRA; match class: 1
CORUM:1297	0.05	0.25	MAP3K5	MKK4-ARRB2-ASK1 complex

Protein 1	Protein 2	Score	Evidence
TNFSF13B	MAP3K15	0.980426	bioplex (TNFSF13B) bioplex_prey
TNFSF13B	MAP3K5	0.977277	bioplex (TNFSF13B) bioplex_prey
TNFSF13B	FAM118A	0.961271	bioplex (TNFSF13B) bioplex_prey
FAM118A	MAP3K5	0.171414	bioplex_prey
FAM118A	MAP3K15	0.171414	bioplex_prey
MAP3K5	MAP3K15	0.171414	bioplex_prey

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