hu.MAP: Complex View

Genename	Complexes	Protein Name	Links
FAM184A	2611	Protein FAM184A	UniProt NCBI
CENPJ	1786 2611 3349	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1)	UniProt NCBI
MAP3K6	2611 3349 3724	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 2)	UniProt NCBI
FLAD1	1786 2611 3349	FAD synthase (EC 2.7.7.2) (FAD pyrophosphorylase) (FMN adenylyltransferase) (Flavin adenine dinucleotide synthase) [Includes: Molybdenum cofactor biosynthesis protein-like region; FAD synthase region]	UniProt NCBI
PLEKHO2	1786 2611 3349	Pleckstrin homology domain-containing family O member 2 (PH domain-containing family O member 2) (Pleckstrin homology domain-containing family Q member 1) (PH domain-containing family Q member 1)	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
OMIM:608393	0.00337	0.2	CENPJ	MICROCEPHALY 6, PRIMARY, AUTOSOMAL RECESSIVE; MCPH6
OMIM:613676	0.00337	0.2	CENPJ	SECKEL SYNDROME 4; SCKL4
GO:0003919	0.0125	0.2	FLAD1	FMN adenylyltransferase activity
HP:0005231	0.0168	0.2	MAP3K6	Chronic gastritis
HP:0002582	0.0168	0.2	MAP3K6	Chronic atrophic gastritis
TF:M01783_0	0.0223	0.8	MAP3K6 FAM184A FLAD1 PLEKHO2	Factor: SP2; motif: GGGCGGGAC; match class: 0
OMIM:210600	0.0235	0.2	CENPJ	Seckel Syndrome
HP:0006442	0.0334	0.2	CENPJ	Hypoplasia of proximal fibula
HP:0007048	0.0334	0.2	CENPJ	Large basal ganglia
HP:0010455	0.0334	0.2	CENPJ	Steep acetabular roof
HP:0006434	0.0376	0.2	CENPJ	Hypoplasia of proximal radius
HP:0030148	0.0376	0.2	CENPJ	Heart murmur
HP:0011342	0.0417	0.2	CENPJ	Mild global developmental delay
HP:0005263	0.0459	0.2	MAP3K6	Gastritis
HP:0012126	0.05	0.2	MAP3K6	Stomach cancer
REAC:196843	0.05	0.2	FLAD1	Vitamin B2 (riboflavin) metabolism
TF:M07080_1	0.05	0.2	MAP3K6	Factor: C/EBPbeta; motif: KATTGCAYMAY; match class: 1
OMIM:251200	0.05	0.2	CENPJ	Primary Microcephaly
GO:0006771	0.05	0.2	FLAD1	riboflavin metabolic process
KEGG:00740	0.05	0.2	FLAD1	Riboflavin metabolism
GO:0008275	0.05	0.2	CENPJ	gamma-tubulin small complex
TF:M04475_1	0.05	0.2	MAP3K6	Factor: NR2F6; motif: NRGGTCAAAGGTCA; match class: 1
MI:hsa-miR-128a	0.05	0.6	FAM184A FLAD1 CENPJ	MI:hsa-miR-128a
HP:0007429	0.05	0.2	CENPJ	Few cafe-au-lait spots
GO:0061511	0.05	0.2	CENPJ	centriole elongation

Protein 1	Protein 2	Score	Evidence
CENPJ	PLEKHO2	0.958175	bioplex (PLEKHO2) bioplex_prey
FLAD1	PLEKHO2	0.843721	bioplex (PLEKHO2) bioplex_prey
PLEKHO2	MAP3K6	0.743196	bioplex (PLEKHO2) bioplex_prey
PLEKHO2	FAM184A	0.555436	bioplex (PLEKHO2) bioplex_prey
CENPJ	FAM184A	0.171414	bioplex_prey
CENPJ	MAP3K6	0.151455	bioplex_prey
FAM184A	MAP3K6	0.151455	bioplex_prey
CENPJ	FLAD1	0.140692	bioplex_prey
FLAD1	FAM184A	0.140692	bioplex_prey
FLAD1	MAP3K6	0.123797	bioplex_prey

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