hu.MAP: Complex View

Human Protein Complex Map

Complex: 4130

Genename	Complexes	Protein Name	Links
TNFSF13B	2401 3724 4130	Tumor necrosis factor ligand superfamily member 13B (B lymphocyte stimulator) (BLyS) (B-cell-activating factor) (BAFF) (Dendritic cell-derived TNF-like molecule) (TNF- and APOL-related leukocyte expressed ligand 1) (TALL-1) (CD antigen CD257) [Cleaved into: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form]	UniProt NCBI
MAP3K5	2401 3724 4130	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5)	UniProt NCBI
MAP3K15	2401 3724 4130	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 3) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15)	UniProt NCBI
FAM160B1	3724 4130	Protein FAM160B1	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0004709	0.000279	0.5	MAP3K15 MAP3K5	MAP kinase kinase kinase activity
GO:0000186	0.000707	0.5	MAP3K15 MAP3K5	activation of MAPKK activity
GO:0004702	0.00633	0.5	MAP3K15 MAP3K5	signal transducer, downstream of receptor, with serine/threonine kinase activity
TF:M00006_1	0.00662	0.5	MAP3K15 TNFSF13B	Factor: MEF-2A; motif: CTCTAAAAATAACYCY; match class: 1
TF:M00124_1	0.0133	1.0	FAM160B1 MAP3K15 MAP3K5 TNFSF13B	Factor: Pbx-1b; motif: NNCATCAATCAANNW; match class: 1
GO:0005057	0.0138	0.5	MAP3K15 MAP3K5	signal transducer activity, downstream of receptor
TF:M04298_0	0.0146	1.0	FAM160B1 MAP3K15 MAP3K5 TNFSF13B	Factor: Cdx-2; motif: GYMATAAAA; match class: 0
KEGG:04672	0.0165	0.25	TNFSF13B	Intestinal immune network for IgA production
CORUM:5691	0.0167	0.25	TNFSF13B	TALL1 homo-oligomer complex
TF:M03880_0	0.0251	0.5	MAP3K5 TNFSF13B	Factor: Myf-5; motif: WGRCAGCTGSWGB; match class: 0
TF:M00941_1	0.0274	0.5	MAP3K5 TNFSF13B	Factor: MEF-2; motif: RGCTATWTTTAR; match class: 1
HPA:026020_01	0.0288	1.0	FAM160B1 MAP3K15 MAP3K5 TNFSF13B	ovary; ovarian stroma cells[Uncertain,Low]
TF:M01300_1	0.0311	0.25	TNFSF13B	Factor: HMGA2; motif: ATATTSSSSNWWATT; match class: 1
GO:0032147	0.036	0.5	MAP3K15 MAP3K5	activation of protein kinase activity
KEGG:05014	0.0374	0.25	MAP3K5	Amyotrophic lateral sclerosis (ALS)
HPA:024010_03	0.039	0.75	FAM160B1 MAP3K15 MAP3K5	nasopharynx; respiratory epithelial cells[Uncertain,High]
KEGG:05323	0.0397	0.25	TNFSF13B	Rheumatoid arthritis
HPA:005010_03	0.0423	0.75	FAM160B1 MAP3K15 TNFSF13B	bronchus; respiratory epithelial cells[Uncertain,High]
TF:M00966_0	0.0432	0.5	FAM160B1 TNFSF13B	Factor: VDR,; motif: RRTGNMCYTNNTGAMCCNYNT; match class: 0
MI:hsa-miR-148b*	0.0452	0.5	FAM160B1 MAP3K15	MI:hsa-miR-148b*
GO:1990604	0.0471	0.25	MAP3K5	IRE1-TRAF2-ASK1 complex
GO:0043405	0.05	0.5	MAP3K15 MAP3K5	regulation of MAP kinase activity
REAC:5676594	0.05	0.25	TNFSF13B	TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
TF:M04281_1	0.05	0.75	FAM160B1 MAP3K15 MAP3K5	Factor: ALX4; motif: NTAATYNAATTAN; match class: 1
MI:hsa-miR-148a*	0.05	0.5	FAM160B1 MAP3K15	MI:hsa-miR-148a*
CORUM:1297	0.05	0.25	MAP3K5	MKK4-ARRB2-ASK1 complex

Edges

Protein 1	Protein 2	Score	Evidence
TNFSF13B	MAP3K15	0.980426	bioplex (TNFSF13B) bioplex_prey
TNFSF13B	MAP3K5	0.977277	bioplex (TNFSF13B) bioplex_prey
TNFSF13B	FAM160B1	0.970701	bioplex (TNFSF13B) bioplex_prey
MAP3K5	MAP3K15	0.171414	bioplex_prey
MAP3K15	FAM160B1	0.151455	bioplex_prey
MAP3K5	FAM160B1	0.151455	bioplex_prey

Images

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hu.MAP: Complex View

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Complex: 4130